COMP360 psilocybin in healthy participants
We want to give people living with mental health challenges better options.
Healthy volunteers study
As part of our psilocybin treatment development programme, we partnered with the Institute of Psychiatry, Psychology & Neuroscience (IoPPN) at King’s College London to run a study with healthy volunteers. The study was a phase 1, double-blind placebo-controlled study with 89 healthy volunteers, aged between 18 and 65 years.
The study demonstrated the feasibility of administering COMP360 psilocybin to up to six healthy participants simultaneously, with 1:1 support. There were no serious adverse events and COMP360 psilocybin was found to be well-tolerated with no clinically-relevant negative effects on cognitive function.
The study was presented at the ACNP 2019 annual meeting (see poster), and at the ASCP 2021 annual meeting (see poster), and published in the peer-reviewed Journal of Psychopharmacology in 2022 (see paper and our press release).